KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIAA1704
All Species:
36.36
Human Site:
S273
Identified Species:
66.67
UniProt:
Q8IXQ4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXQ4
NP_061029.2
340
38142
S273
S
Y
N
E
S
K
R
S
E
S
L
M
D
I
H
Chimpanzee
Pan troglodytes
XP_509661
340
38139
S273
S
Y
N
E
S
K
R
S
E
S
L
M
D
I
H
Rhesus Macaque
Macaca mulatta
XP_001094145
344
38614
S277
S
Y
N
E
S
K
R
S
E
S
L
M
D
M
H
Dog
Lupus familis
XP_851499
342
38712
S275
S
Y
N
E
S
K
R
S
E
S
L
M
D
I
H
Cat
Felis silvestris
Mouse
Mus musculus
Q69ZC8
346
38936
S279
S
Y
N
E
S
K
R
S
E
S
L
M
D
I
H
Rat
Rattus norvegicus
Q4V893
348
39156
S281
S
Y
N
E
S
K
R
S
E
S
L
M
D
I
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514535
347
38704
S280
S
Y
N
D
S
K
R
S
E
S
L
M
D
I
H
Chicken
Gallus gallus
NP_001006270
350
39239
S283
S
Y
N
E
S
K
R
S
E
S
L
M
D
I
H
Frog
Xenopus laevis
NP_001089474
337
37926
S270
T
Y
N
D
S
R
R
S
E
S
L
I
D
L
H
Zebra Danio
Brachydanio rerio
NP_001003473
405
45367
R337
S
K
Y
N
E
S
K
R
G
E
S
L
I
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_996214
349
39457
K286
S
L
V
E
L
H
Q
K
K
L
R
K
E
Q
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q93591
297
33204
E243
I
H
Q
K
K
R
D
E
K
V
K
D
A
G
Y
Sea Urchin
Strong. purpuratus
XP_796639
403
45460
V327
D
K
R
L
A
D
M
V
A
K
H
N
E
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.3
91.5
N.A.
89.5
87.3
N.A.
64.2
68.8
63.2
47.1
N.A.
26.9
N.A.
27.6
37.9
Protein Similarity:
100
100
98.5
96.1
N.A.
93.6
93.3
N.A.
75.2
80
75.8
60.2
N.A.
41.5
N.A.
44.7
53.8
P-Site Identity:
100
100
93.3
100
N.A.
100
100
N.A.
93.3
100
66.6
6.6
N.A.
13.3
N.A.
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
20
N.A.
33.3
N.A.
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
8
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
16
0
8
8
0
0
0
0
8
70
0
0
% D
% Glu:
0
0
0
62
8
0
0
8
70
8
0
0
16
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% G
% His:
0
8
0
0
0
8
0
0
0
0
8
0
0
0
70
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
8
8
54
0
% I
% Lys:
0
16
0
8
8
62
8
8
16
8
8
8
0
0
8
% K
% Leu:
0
8
0
8
8
0
0
0
0
8
70
8
0
8
8
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
62
0
8
0
% M
% Asn:
0
0
70
8
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
8
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
8
0
0
16
70
8
0
0
8
0
0
0
8
% R
% Ser:
77
0
0
0
70
8
0
70
0
70
8
0
0
8
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% T
% Val:
0
0
8
0
0
0
0
8
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
70
8
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _